Oxidative stress is important in the pathogenesis of stress‑related mucosal disease
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چکیده
منابع مشابه
Oxidative stress is more important than acid in the pathogenesis of reflux oesophagitis in rats.
BACKGROUND Although antisecretory medications such as histamine type II receptor antagonists or proton pump inhibitors have been used to treat reflux oesophagitis, a considerable number of patients do not achieve complete mucosal healing or suffer from either sustained symptoms or ensuing complications, suggesting other damaging factors or impaired mucosal resistance are also involved in the pa...
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The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor. There is a growing belief, however, that obesity, specially visceral obe...
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Periodontal disease is a chronic inflammatory disease caused by gram-negative bacteria, characterized by gingival inflammation and alveolar bone resorption. In the pathogenesis of periodontal disease free radicals and oxidative stress play a significant role. Free radicals are frequently formed as metabolic by-products and their overproduction leads to cell damage and the development of oxidati...
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Skin is the largest body organ that serves as an important environmental interface providing a protective envelope that is crucial for homeostasis. On the other hand, the skin is a major target for toxic insult by a broad spectrum of physical (i.e. UV radiation) and chemical (xenobiotic) agents that are capable of altering its structure and function. Many environmental pollutants are either the...
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M. Bansal and N. Kaushal, Oxidative Stress Mechanisms and their Modulation, DOI 10.1007/978-81-322-2032-9_2, © Springer India 2014 Oxidative stress has been well implicated in the pathogenesis of various human diseases. Presently mechanistic considerations of the oxidative stress pathogenesis in most vital organ systems, e.g., nervous system, cardiovascular system, male/ female reproductive sys...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2020
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2020.9211